Odysséa supports Gustave Roussy's COMPASS project
In 2021 Odysséa was able to participate in the financing of Gustave Roussy's COMPASS [1] project. COMPASS aims to identify new therapeutic strategies for a very harmful type of breast cancer: triple-negative cancer.
Odysséa supports Gustave Roussy's COMPASS project
Triple-negative cancer unfortunately remains a difficult cancer to treat, with a high risk of relapse and a very limited number of effective therapies. Triple-negative cancer is characterized by the absence of expression of estrogen and progesterone hormone receptors and the absence of overexpression of HER-2 growth factor.
In numbers, triple-negative cancer is:
- 15% of breast cancer cases, i.e. 7,500 women affected each year in France and 140,000 women worldwide.
- 40% of affected women under the age of 40.
- 1.200 women in France face early treatment failure
With his COMPASS project, Gustave Roussy is committed to identifying new effective therapeutic strategies for women with triple-negative breast cancer. Led by Dr. Barbara Pistilli, COMPASS aims to determine over the next 3 years the most effective potential strategies in the treatment of early relapses of triple-negative breast cancer. Approximately 200 patients will be included in the COMPASS program over 3 years.
The 3-year program:
- 2022: Identify a combination of bispecific antibodies or conjugated antibodies and immunotherapy that could improve survival.
- 2023 : Study combinations with CAR-T cells, an innovative strategy already used in other cancers such as lymphomas.
- 2024: Identify biomarkers predictive of early relapse.